{"id":192972,"date":"2016-10-27T11:18:57","date_gmt":"2016-10-27T15:18:57","guid":{"rendered":"http:\/\/www.rochester.edu\/newscenter\/?p=192972"},"modified":"2016-11-01T12:39:53","modified_gmt":"2016-11-01T16:39:53","slug":"breakthrough-adds-new-color-to-ultrasound-makes-images-easier-to-interpret-192972","status":"publish","type":"post","link":"https:\/\/www.rochester.edu\/newscenter\/breakthrough-adds-new-color-to-ultrasound-makes-images-easier-to-interpret-192972\/","title":{"rendered":"Breakthrough adds new color to ultrasound"},"content":{"rendered":"<figure id=\"attachment_193772\" aria-describedby=\"caption-attachment-193772\" style=\"width: 1000px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-193772\" src=\"https:\/\/www.rochester.edu\/newscenter\/wp-content\/uploads\/2016\/10\/color-ultrasound-parker.jpg\" alt=\"grey and color images from ultrasond\" width=\"1000\" height=\"794\" srcset=\"https:\/\/www.rochester.edu\/newscenter\/wp-content\/uploads\/2016\/10\/color-ultrasound-parker.jpg 1000w, https:\/\/www.rochester.edu\/newscenter\/wp-content\/uploads\/2016\/10\/color-ultrasound-parker-630x500.jpg 630w, https:\/\/www.rochester.edu\/newscenter\/wp-content\/uploads\/2016\/10\/color-ultrasound-parker-768x610.jpg 768w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><figcaption id=\"caption-attachment-193772\" class=\"wp-caption-text\">This image, from the lab of Professor Kevin Parker, shows the color imaging possible with his H-scan format compared to traditional ultrasound imaging around it, showing only shades of gray. Red vs. blue indicates different types of scatterers.<\/figcaption><\/figure>\n<p>Inspired by a 19<sup>th<\/sup>-century set of mathematical functions, Ä¢¹½´«Ã½ researcher <strong><a href=\"http:\/\/www.ece.rochester.edu\/projects\/Parker\/Parker.html\">Kevin Parker<\/a><\/strong> has devised a way to incorporate new color identifications in ultrasound medical images, making it easier to differentiate fine details that currently appear as indistinguishable objects in shades of gray.<\/p>\n<p>The new imaging format would be especially valuable in helping physicians interpret ultrasound images of soft tissue, including muscle, glands, and organs such as the liver.<\/p>\n<p>\u201cThis has been a great goal\u201d of ultrasound research since the 1970s, said Parker, the William F. May Professor of Engineering. The technology, <strong><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27223245\">described in a paper in <em>Physics in Medicine &amp; Biology<\/em>,<\/a><\/strong> provides more detailed soft tissue images than other attempts, based on quantitative backscattered imaging, Parker said.<\/p>\n<p>Ultrasound uses pulses of high-frequency sound waves that bounce back echoes when they strike cells or arteries. These echoes are also known as scattered waves. The bouncing back gives the ultrasound image its features. With few exceptions \u2013 such as Doppler-enhanced ultrasound imaging of blood flow \u2013 those features consist of varying shades of black, white and gray reflecting different densities.<\/p>\n<div class=\"embed-container\">\n<iframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\/\/www.youtube.com\/embed\/Q6gSDfTwxcA\" frameborder=\"0\" allowfullscreen><\/iframe>\n<\/div>\n<p>\u201cIf you look at an ultrasound image of the liver, there are so many things in there \u2013 veins, arteries, biliary ducts, liver cells, perhaps some scar tissue \u2013 and they\u2019re all just displayed as black and white blobs,\u201d Parker said. \u201cIf there\u2019s a large artery, it\u2019s easy to see the wall and the blood inside. But at the finer levels of detail, it is often impossible to tell if you\u2019re looking at a smaller artery or 10 little cells.\u201d<\/p>\n<p>A set of mathematical functions &#8212; devised in 1890 by the great mathematician Charles Hermite of France and rarely used in engineering &#8212; provided Parker with a way to approach this problem. He came across the functions while perusing a handbook of transforms and applications, and immediately recognized that Hermite\u2019s functions closely approximated ultrasound pulses.<\/p>\n<p>\u201cI realized if we used these, it would make our analyses of ultrasound scattering easier,\u201d Parker said. \u201cSo now, instead of ultrasound images showing all of these tissue structures as black and white objects, we can now classify them mathematically (by their size) and assign unique colors to unique types of scatterers.\u201d<\/p>\n<figure id=\"attachment_193002\" aria-describedby=\"caption-attachment-193002\" style=\"width: 522px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-193002\" src=\"https:\/\/www.rochester.edu\/newscenter\/wp-content\/uploads\/2016\/10\/Figure7-for-story-522x630.jpg\" alt=\"In these images from the lab of Professor Kevin Parker, an increase in fatty lipids in liver tissue (figures a and b) is shown in blue using the H-scan format, compared to normal tissue (figures c and d).\" width=\"522\" height=\"630\" srcset=\"https:\/\/www.rochester.edu\/newscenter\/wp-content\/uploads\/2016\/10\/Figure7-for-story-522x630.jpg 522w, https:\/\/www.rochester.edu\/newscenter\/wp-content\/uploads\/2016\/10\/Figure7-for-story-768x926.jpg 768w, https:\/\/www.rochester.edu\/newscenter\/wp-content\/uploads\/2016\/10\/Figure7-for-story-849x1024.jpg 849w, https:\/\/www.rochester.edu\/newscenter\/wp-content\/uploads\/2016\/10\/Figure7-for-story.jpg 1533w\" sizes=\"auto, (max-width: 522px) 100vw, 522px\" \/><figcaption id=\"caption-attachment-193002\" class=\"wp-caption-text\">In these images from the lab of Professor Kevin Parker, an increase in fatty lipids in liver tissue (figures a and b) is shown in blue using the H-scan format, compared to normal tissue (figures c and d).<\/figcaption><\/figure>\n<p>Working with UR Ventures, the University\u2019s technology transfer office, Parker has secured a provisional patent on the technology, called H-scan.<\/p>\n<p>\u201cIt can be implemented on ultrasound scanners, so I am hoping companies will license it, and put it into clinical trials,\u201d Parker said.<\/p>\n<p>\u201cBy letting us see things we can\u2019t see now, it could be very important to individual patients.\u201d<\/p>\n<p>Working in his lab with PhD student Juvenal Ormachea, Parker continues to investigate the parameters of ultrasound and how other processes could further enhance the technology as a diagnostic tool.<\/p>\n<p>Since the early 1960s, Ä¢¹½´«Ã½ researchers such Raymond Gramiak, Robert Waag, Edwin Carstensen, and Parker have produced pioneering clinical and technological advances in diagnostic ultrasound imaging. The<strong> <a href=\"https:\/\/www.rochester.edu\/rcbu\/\">Rochester Center for Biomedical Ultrasound<\/a><\/strong>, formed in 1986, includes nearly 100 researchers, including visiting scientists from around the country.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Rochester engineering professor Kevin Parker has devised a way to differentiate fine details in medical ultrasound images that currently appear as indistinguishable objects in shades of gray.<\/p>\n","protected":false},"author":286,"featured_media":193762,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[116],"tags":[18742,19382,29502,18632,22532,18572],"class_list":["post-192972","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sci-tech","tag-department-of-biomedical-engineering","tag-department-of-electrical-and-computer-engineering","tag-featured-post-side","tag-hajim-school-of-engineering-and-applied-sciences","tag-kevin-parker","tag-research-finding"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Breakthrough adds new color to ultrasound<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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